Biomedical imaging is an emerging multidisciplinary field that allows visualization, characterization, and measurement of biological processes at the molecular and cellular levels in humans and other living systems. Rather than replacing existing modalities such as computed tomography (CT) or magnetic resonance imaging (MRI), biomedical imaging aims to add functional and molecular specificity to anatomical information. This provides a more comprehensive understanding of disease processes by revealing molecular alterations and pathways before anatomical changes occur.

Molecular ImagingModalities

Several techniques are used for Molecular Imaging including positron emission tomography (PET), single-photon emission computed tomography (SPECT), bioluminescence imaging, fluorescent imaging, and magnetic resonance imaging (MRI). Each has its own strengths and limitations. PET and SPECT are unique in being able to detect molecular probes labeled with radioactive isotopes, achieving very high sensitivity down to the picomolar level. However, radioactive labels also mean additional regulatory hurdles and safety considerations. Optical imaging modalities like bioluminescence and fluorescence offer high throughput and relatively low cost but are limited by optical scattering to small animal research. MRI does not use ionizing radiation but may have lower sensitivity for molecular probes than nuclear techniques. The appropriate modality depends on the target, application, and diagnostic or research question.

Get More Insights On, Molecular Imaging