2-aminothiazole storage method, also known as α-methylpyridine, is a colorless oily liquid with a strong unpleasant odor of pyridine, used as a raw material for synthetic drugs, dyes, resins, fertilizer synergists, herbicides, livestock repellents, rubber accelerators, dye intermediates, etc. Do you know how it's synthesized and what its dangers are? Here, let's take a look.

Synthesis methods shared by pyridine manufacturers

Pyridine and methylpyridine are commonly recovered from coking byproducts and are distributed in coke oven gas, crude benzene and tar. In general, the boiling point of pyridine hydrate transferred from gas to ammonium sulfide mother liquor is very low, between 95-97℃, and the content of 2-aminothiazole storage method in the recovered crude light pyridine base is about 15 percent. Further distillation results in the 2-aminothiazole storage method. As the use of pyridine and methylpyridine expanded, the synthesis of pyridine and methylpyridine developed. About 95 percent of pyridine and pyridine compounds abroad are produced by synthesis. The main synthesis methods are acetaldehyde, acetylene, acrylonitrile and so on.

Acetaldehyde process: acetaldehyde, formaldehyde and ammonia reaction, the main products are 2-aminothiazole storage method, 3-methylpyridine and 4-methylpyridine.

Acetylene process: Acetylene reacts with ammonia, and the main products are 2-aminothiazole storage method and 4-methylpyridine.

Ethylene process: ethylene reacts with ammonia, and the main products are 2-aminothiazole storage method and 2-methyl-5-ethylpyridine.

Acrylonitrile process: acrylonitrile reacts with excess acetone, and the main product is 2-aminothiazole storage method. In addition, acrolein reacts with ammonia to form 3-methylpyridine.

Harm:

2-aminothiazole storage method

Health hazard: This product is irritating and has damage to the nervous system, liver and kidney. After exposure, eyes, skin and mucous membranes may be irritated, and cause headache, dizziness, nausea, vomiting, mental retardation, abdominal pain, diarrhea, etc. Fire hazard: This product is inflammable and irritating.

Skin contact: Remove contaminated clothing and rinse skin completely with soapy water and clean water. Eye contact: Lift eyelids and rinse with running water or saline. Seek medical attention.

Inhalation: Move quickly from the scene to fresh air. Keep your airway clear. Give oxygen when breathing is difficult. If breathing stops, give artificial respiration immediately. Seek medical attention.

Ingestion: Drinking enough warm water to induce vomiting. Seek medical attention.

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