DNA encoded library refers to a collection of small molecules or peptides that have been chemically encoded with identifiable DNA tags. These libraries can be rapidly screened against biological targets of interest in order to identify potential lead compounds for drug development. DNA encoded libraries have emerged as a powerful tool for drug discovery in pharmaceutical industry as they allow for highly multiplexed and parallel screening of millions of compounds. Encoding molecules with DNA allows precise tracking of each compound through the selection and amplification process.
The demand for DNA Encoded Library is growing steadily as they enable simultaneous screening of hundreds of thousands to millions of compounds against disease relevant biological targets. This has significantly improved hit rates and accelerated the drug discovery process compared to conventional high throughput screening methods.
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