Roots Analysis has done a detailed study on “Global Regulatory T-Cell (Tregs) Therapies Market, covering key aspects of the industry’s evolution and identifying potential future growth opportunities.


Given the various benefits offered, including high target specificity, customization potential and ability to generate immunological memory, regulatory Treg cell therapies have garnered significant attention among key industry stakeholders for the treatment of various oncological and non-oncological disease indications.



Key Market Insights


  • More than 150 industry players across the world are presently engaged in evaluating the potential of nearly 300 next generation immune checkpoint modulators for the treatment of multiple disease indications
  • The pipeline features a variety of marketed / clinical stage therapies, targeting a number of different types of immune checkpoints and being investigated for administration via different routes
  • In the last few years, over 600 clinical studies of various types of immune checkpoint modulation-based therapies, involving nearly 90,000 patients across different centers / hospitals, have been initiated worldwide
  • In the pursuit of obtaining an edge within this emerging and highly competitive market landscape, developers are actively exploring the therapeutic potential of novel immune checkpoints, beyond PD-L1, PD-1 and CTLA-4
  • Over time, big pharma players have initiated product development programs focused on immune checkpoint modulation for treating various oncological indications, investing significant capital, time and effort
  • Several organizations have extended financial support to aid research efforts in this domain; the current focus is on investigation of novel immune checkpoint pathways / targets
  • The growing interest in this field is also reflected by the 120+ partnerships have been signed in the last two years, involving both international and indigenous stakeholders
  • The future market, based on the revenue generation potential of marketed and late stage therapies, is anticipated to be distributed across different disease areas, mechanisms and key geographical regions
  • In the long term, the opportunity is likely to be segmented across diverse therapeutic modalities, immune checkpoint targets and routes of administration


One of the key objectives of the report was to estimate the existing market size and identify potential growth opportunities associated with Treg cell therapies, over the coming decade. The report also includes likely sales forecasts of Treg cell therapies that are in the mid to late stages of development.


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Table of Contents


  1. Preface

    2. Executive Summary

  2. Introduction

  3. Current Market Landscape

  4. Therapy Profiles

  5. Clinical Trial Analysis

  6. Partnerships and Collaborations


  1. Funding and Investment Analysis


  1. Porter’s Five Analysis

  2. Company Profiles

  3. Market Sizing and Opportunity Analysis

  4. Conclusion

  5. Executive Insights


  1. Appendices



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